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Moracin C
CAS No. 69120-06-5
Moracin C ( —— )
产品货号. M37739 CAS No. 69120-06-5
Moracin C，一种天然产物，是一种抗炎剂。Moracin C 抑制 LPS 激活的活性氧 (ROS) 和一氧化氮 (NO) 从细胞中释放。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥2558 | 有现货 |
|
| 5MG | ￥4142 | 有现货 |
|
| 10MG | ￥6032 | 有现货 |
|
| 25MG | ￥9071 | 有现货 |
|
| 50MG | ￥12199 | 有现货 |
|
| 100MG | ￥15912 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Moracin C
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Moracin C，一种天然产物，是一种抗炎剂。Moracin C 抑制 LPS 激活的活性氧 (ROS) 和一氧化氮 (NO) 从细胞中释放。
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产品描述Moracin C, a natural product, is an anti-inflammatory agent. Moracin C inhibits LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) release from cells.
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体外实验RT-PCR Cell Line:RAW 264.7 macrophages Concentration:1, 10, 25, 50 μM Incubation Time:2 h Result:Inhibited LPS-induced mRNA expression of iNOS and COX-2.Western Blot Analysis Cell Line:RAW 264.7 macrophages Concentration:1, 10, 25, 50 μM Incubation Time:2 h Result:Inhibited LPS-induced TLR4 expression and NF-κB activation.Reduced phosphorylated p38, ERK and JNK levels.
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体内实验Animal Model:Mice (PK Assay)Dosage:100 mg/kg Administration:Oral gavage Result:Pharmacokinetic profile of Moracin C.
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同义词——
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通路Immunology/Inflammation
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靶点ROS
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受体ROS | NO Synthase
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研究领域——
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适应症——
化学信息
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CAS Number69120-06-5
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分子量310.34
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分子式C19H18O4
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 250 mg/mL (805.57 mM; 超声助溶 )
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SMILESCC(C)=CCc1c(O)cc(cc1O)-c1cc2ccc(O)cc2o1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Yao X, et al. Moracin C, A Phenolic Compound Isolated from Artocarpus heterophyllus, Suppresses Lipopolysaccharide-Activated Inflammatory Responses in Murine Raw264.7 Macrophages. Int J Mol Sci. 2016 Jul 25;17(8):1199. ?
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